ASPIRIN(75MG) + CLOPIDOGREL(150MG)

Schedule H · Prescription required

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About ASPIRIN(75MG) + CLOPIDOGREL(150MG)

Introduction

This medicine is a combination of two antiplatelet agents: Aspirin (75mg) and Clopidogrel (150mg). It is commonly prescribed to prevent blood clots in patients with heart and blood vessel conditions. This combination works by reducing the ability of blood platelets to stick together, thereby lowering the risk of harmful clot formation.

Uses

This combination is used to prevent heart attack and stroke in patients with acute coronary syndrome, unstable angina, or those who have undergone heart procedures like angioplasty or stent placement. It is prescribed for patients with existing cardiovascular disease to reduce the risk of blood clot-related complications. It may also be used in patients with peripheral artery disease or after certain types of stroke.

Benefits

The combination provides enhanced protection against blood clot formation compared to either medicine alone. It significantly reduces the risk of heart attack, stroke, and cardiovascular death in high-risk patients. By preventing platelets from clumping together, it helps maintain smooth blood flow through arteries. This dual antiplatelet therapy is particularly beneficial in the critical period following a heart event or cardiovascular procedure.

Side effects

Common side effects include increased bleeding tendency, bruising easily, nosebleeds, stomach upset, indigestion, and headache. Some patients may experience blood in urine or stools, or prolonged bleeding from cuts. Most side effects are mild and temporary. However, contact your doctor immediately if you notice unusual bleeding, severe stomach pain, black tarry stools, blood in vomit, severe headache, or signs of allergic reaction. Regular monitoring may be needed during treatment.

How to use

Take this medicine exactly as prescribed by your doctor. It is usually taken once daily, preferably at the same time each day. Swallow the tablet whole with water; do not crush, chew, or break it. It can be taken with or without food, but taking it with food may help reduce stomach upset. Do not stop taking this medicine suddenly without consulting your doctor, as this may increase your risk of blood clots.

How it works

This medicine contains two antiplatelet agents that work through different mechanisms. Aspirin blocks the enzyme cyclooxygenase, preventing the formation of thromboxane A2, which causes platelets to stick together. Clopidogrel blocks a different receptor on platelets called P2Y12, preventing platelet activation. Together, they provide more effective prevention of blood clot formation than either medicine alone, reducing the risk of cardiovascular events.

Safety advice

Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. Avoid alcohol consumption as it may increase the risk of stomach bleeding. Use with caution in patients with liver or kidney problems; dose adjustment may be needed. This medicine increases bleeding risk, so inform all healthcare providers and dentists before any surgery or procedure. Avoid activities with high injury risk. Do not take with other blood thinners unless advised by your doctor. Report any signs of unusual bleeding immediately. Patients with history of stomach ulcers, bleeding disorders, or allergies to aspirin or NSAIDs should inform their doctor before use.

This information is for general awareness only and is not a substitute for professional medical advice. Always verify dosage and suitability with your doctor or our registered pharmacist.

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