GLIBENCLAMIDE(5MG) + METFORMIN(500MG) + PIOGLITAZONE(15MG)

This medicine is prescribed for the treatment of type 2 diabetes mellitus in adults. It is used when blood sugar levels are not adequately controlled by diet, exercise, and treatment with one or two antidiabetic medicines alone. It helps improve glycemic control by working on multiple pathways that affect blood sugar regulation.

This combination works through three complementary mechanisms. Glibenclamide stimulates the pancreas to release more insulin. Metformin decreases glucose production in the liver, reduces glucose absorption in the intestines, and improves insulin sensitivity in muscles. Pioglitazone makes body tissues more sensitive to insulin and helps glucose enter cells more effectively. Together, these actions help lower and maintain blood sugar levels throughout the day.

Common side effects include low blood sugar (hypoglycemia), nausea, stomach upset, diarrhea, weight gain, and headache. Some patients may experience bloating, metallic taste in mouth, or mild swelling in hands or feet. Most side effects are mild and temporary, improving as your body adjusts to the medicine. Contact your doctor if you experience severe hypoglycemia symptoms, persistent stomach pain, unusual tiredness, yellowing of eyes or skin, or difficulty breathing.

Take this medicine exactly as prescribed by your doctor. It is usually taken with meals to reduce stomach upset and lower the risk of low blood sugar. Swallow the tablet whole with water; do not crush or chew it. Take it at the same time each day to help you remember. Never skip meals after taking this medicine. Do not change the dose or stop taking it without consulting your doctor. Always follow your doctor's or pharmacist's specific instructions.

Avoid alcohol as it may increase the risk of low blood sugar and lactic acidosis. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding, as this medicine is generally not recommended. Caution is needed in patients with kidney or liver problems; regular monitoring may be required. This medicine may cause dizziness or low blood sugar; avoid driving if affected. Inform your doctor about all other medicines you take, especially other diabetes medicines, heart medications, or steroids. Regular blood sugar monitoring and periodic kidney, liver function tests are important. Maintain a healthy diet and exercise routine as advised.