GLICLAZIDE(40MG) + METFORMIN(500MG)

This combination medicine is prescribed for: - Treatment of type 2 diabetes mellitus in adults - Managing blood sugar levels when single drug therapy is inadequate - Improving glycemic control in patients not adequately controlled on either Gliclazide or Metformin alone - As part of comprehensive diabetes management along with proper diet and exercise

This combination works through two complementary mechanisms. Gliclazide is a sulfonylurea that stimulates the beta cells in the pancreas to release more insulin, helping cells absorb glucose from the blood. Metformin is a biguanide that decreases glucose production in the liver, reduces glucose absorption from the intestines, and improves insulin sensitivity in muscles and fat tissues. Together, they effectively lower blood sugar levels through multiple pathways.

Common side effects include nausea, vomiting, diarrhea, stomach upset, loss of appetite, metallic taste in mouth, and headache. Low blood sugar (hypoglycemia) may occur, causing sweating, dizziness, weakness, or hunger. Most side effects are mild and temporary, settling as your body adjusts. However, contact your doctor if you experience persistent vomiting, severe stomach pain, unusual tiredness, yellowing of eyes or skin, or signs of lactic acidosis (rare but serious).

Take this medicine exactly as prescribed by your doctor. It is usually taken with meals to reduce stomach upset and minimize the risk of low blood sugar. Swallow the tablet whole with water; do not crush or chew. Take at the same time each day for best results. Never skip meals after taking this medicine. Do not adjust the dose on your own. Always follow your doctor's or pharmacist's specific instructions regarding timing and dosage.

Alcohol: Avoid alcohol as it increases the risk of low blood sugar and lactic acidosis. Pregnancy: Not recommended during pregnancy; consult your doctor for safer alternatives. Insulin is usually preferred for diabetes during pregnancy. Breastfeeding: Consult your doctor; may not be recommended while breastfeeding. Kidney: Use with caution in kidney disease; dose adjustment or alternative treatment may be needed. Regular kidney function monitoring is important. Liver: Avoid in severe liver disease due to risk of lactic acidosis. Driving: May cause low blood sugar or dizziness; avoid driving if you experience these symptoms. Monitoring: Regular blood sugar and HbA1c monitoring required. Inform all healthcare providers about this medication before any surgery or medical procedures.