METHOTREXATE(5MG)

Schedule H · Prescription required

Every brand and generic we stock with the composition METHOTREXATE(5MG). Compare prices and pick the best-value option — same salt, same effect.

About METHOTREXATE(5MG)

Introduction

Methotrexate 5mg is a medication that belongs to a group of medicines called disease-modifying antirheumatic drugs (DMARDs) and antimetabolites. It contains methotrexate as the active ingredient, which is used to treat various conditions including autoimmune diseases and certain types of cancer. This medicine works by suppressing the overactive immune system and slowing down the growth of rapidly dividing cells.

Uses

Methotrexate is prescribed for rheumatoid arthritis, psoriasis, and psoriatic arthritis when other treatments have not worked adequately. It is also used to treat certain types of cancer including acute lymphoblastic leukemia, non-Hodgkin's lymphoma, and osteosarcoma. Additionally, it may be prescribed for severe cases of Crohn's disease and other autoimmune conditions. The dosage and frequency vary significantly depending on the condition being treated.

Benefits

For autoimmune conditions like rheumatoid arthritis, methotrexate helps reduce joint pain, swelling, and stiffness, preventing long-term joint damage and improving quality of life. In psoriasis, it helps clear skin lesions and reduces inflammation. For cancer treatment, it helps slow or stop the growth of cancer cells. The medicine can significantly improve symptoms and help patients maintain better function in their daily activities when used as prescribed.

Side effects

Common side effects include nausea, vomiting, loss of appetite, mouth sores, stomach upset, and tiredness. Some patients may experience headache, dizziness, or hair thinning. Less common but important side effects include fever, unusual bruising or bleeding, dark urine, and persistent cough. Most side effects are mild and manageable. However, contact your doctor if you experience severe symptoms such as difficulty breathing, severe stomach pain, or signs of infection.

How to use

Take methotrexate exactly as prescribed by your doctor. For arthritis and psoriasis, it is usually taken once weekly on the same day each week, NOT daily. Swallow the tablet whole with water. It can be taken with or without food, but taking it with food may help reduce stomach upset. Never adjust the dose yourself. Your doctor may also prescribe folic acid supplements to reduce side effects. Always follow your doctor's specific instructions carefully.

How it works

Methotrexate works by blocking an enzyme called dihydrofolate reductase, which cells need to make DNA and multiply. In cancer treatment, this prevents cancer cells from growing and spreading. For autoimmune diseases like rheumatoid arthritis and psoriasis, it suppresses the overactive immune system that causes inflammation and tissue damage. By reducing immune system activity and cell multiplication, it helps control symptoms and prevents disease progression.

Safety advice

Avoid alcohol completely as it increases the risk of liver damage. This medicine can cause serious birth defects; women and men must use effective contraception during treatment and for several months after stopping. Do not use during pregnancy or breastfeeding. Inform your doctor about any kidney or liver problems as dose adjustments may be needed. Regular blood tests are essential to monitor liver function, kidney function, and blood counts. Avoid contact with people who have infections. Do not take NSAIDs or other medicines without consulting your doctor due to potential interactions. If driving, be cautious as dizziness may occur.

This information is for general awareness only and is not a substitute for professional medical advice. Always verify dosage and suitability with your doctor or our registered pharmacist.

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