SITAGLIPTIN(100MG) + METFORMIN(1000MG) + PIOGLITAZONE(15MG)

This combination medicine is prescribed for the treatment of type 2 diabetes mellitus in adults. It is used when blood sugar levels are not adequately controlled with diet, exercise, and treatment with two of these medicines alone. It helps improve blood sugar control as part of a comprehensive diabetes management plan that includes proper diet and regular physical activity.

This combination works through three complementary mechanisms. Sitagliptin increases insulin release and decreases glucagon secretion in a glucose-dependent manner. Metformin reduces glucose production in the liver and improves insulin sensitivity in muscles. Pioglitazone helps body cells use insulin more effectively by making them more sensitive to insulin. Together, these actions help lower and maintain blood sugar levels throughout the day.

Common side effects include nausea, vomiting, diarrhea, stomach upset, headache, metallic taste in the mouth, and mild weight gain. Some patients may experience swelling in hands or feet, cold-like symptoms, or muscle pain. Rarely, low blood sugar (hypoglycemia) may occur, especially when combined with other diabetes medicines. Most side effects are mild and temporary. Contact your doctor if side effects persist or if you experience severe abdominal pain, unusual tiredness, or difficulty breathing.

Take this medicine exactly as prescribed by your doctor. It is usually taken once or twice daily with meals to reduce stomach upset and improve absorption. Swallow the tablet whole with water; do not crush, chew, or break it. Take it at the same time each day for best results. Never adjust the dose on your own. Continue following your prescribed diet and exercise plan while taking this medicine.

Avoid alcohol as it may increase the risk of lactic acidosis and low blood sugar. Inform your doctor if you have kidney, liver, or heart problems before starting this medicine. Not recommended during pregnancy and breastfeeding; consult your doctor for alternatives. Monitor blood sugar regularly and watch for signs of low blood sugar. This medicine may cause dizziness or low blood sugar, so be cautious while driving. Inform your doctor about all other medicines you take. Regular monitoring of kidney function, liver function, and heart health is important during treatment.