TOFACITINIB(5MG)

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About TOFACITINIB(5MG)

Introduction

Tofacitinib 5mg is a medication belonging to a class of drugs called Janus kinase (JAK) inhibitors. It is used to treat certain autoimmune and inflammatory conditions by reducing the activity of the immune system. This generic medicine contains tofacitinib as its active ingredient and is available in extended-release formulation.

Uses

Tofacitinib is prescribed for the treatment of: - Rheumatoid arthritis (moderate to severe) in adults who have not responded well to other treatments - Psoriatic arthritis in adults - Ulcerative colitis (moderate to severe) when other treatments have not worked - Ankylosing spondylitis in adults - Polyarticular course juvenile idiopathic arthritis in children aged 2 years and older

Benefits

Tofacitinib helps reduce joint pain, swelling, and stiffness in arthritis conditions, improving physical function and quality of life. For ulcerative colitis, it helps reduce symptoms like bloody diarrhea, abdominal pain, and urgency. The medicine works to control inflammation and slow down disease progression. Regular use as prescribed helps patients manage their condition better and maintain daily activities with reduced symptoms.

Side effects

Common side effects include upper respiratory tract infections, headache, diarrhea, nausea, and increased risk of infections. Some patients may experience high blood pressure, changes in blood cholesterol levels, or abnormal liver function tests. Serious but less common effects include serious infections, blood clots, and changes in blood cell counts. Most side effects are mild and temporary. Contact your doctor if you develop fever, persistent cough, unusual tiredness, or signs of infection.

How to use

Take tofacitinib exactly as prescribed by your doctor. The 11mg extended-release tablet is usually taken once daily. Swallow the tablet whole with water; do not crush, break, or chew it. It can be taken with or without food, but taking it at the same time each day helps maintain consistent levels. Do not stop taking this medicine suddenly without consulting your doctor, even if you feel better.

How it works

Tofacitinib works by blocking the action of specific enzymes called Janus kinases (JAK) inside immune cells. These enzymes play a key role in sending signals that cause inflammation in the body. By inhibiting JAK enzymes, tofacitinib reduces the production of inflammatory chemicals and decreases the overactive immune response responsible for joint damage and inflammation in various conditions.

Safety advice

Pregnancy/Breastfeeding: Not recommended during pregnancy or breastfeeding; consult your doctor for alternatives. Alcohol: Limit alcohol consumption as it may increase the risk of liver problems. Kidney/Liver: Inform your doctor if you have kidney or liver disease; dose adjustment may be needed. Driving: Generally safe, but if you feel dizzy, avoid driving. Infections: Avoid this medicine if you have active serious infections. Get vaccinations up to date before starting treatment. Blood clots: Inform your doctor if you have a history of blood clots or cardiovascular disease. Regular monitoring of blood tests is required during treatment.

This information is for general awareness only and is not a substitute for professional medical advice. Always verify dosage and suitability with your doctor or our registered pharmacist.

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